Investors often look to insider trading activity as a potential indicator of where a stock may be headed. Stryker Corp (SYK) has recently seen notable insider movement that could influence investor sentiment.
On November 20, 2025, Wells Preston Wendell sold Stryker shares valued at $60,370. At a transaction price of $365.88 per share, Wendell offloaded 165 shares, bringing his total holdings down to 6,694 shares worth roughly $2.49 million. In a separate but related transaction, Preston Wells purchased 165 shares, also involving proceeds of more than $60,370, adding another layer of interest to recent insider behavior.
Before these trades, Berry William E Jr, the company’s VP and Chief Accounting Officer, sold 1,953 shares for approximately $713,802 at $365.49 per share. Following this sale, his remaining holdings stood at 1,953 shares, valued at about $1.05 million.
Analyst Sentiment
Analyst coverage has also shifted in recent months. Rothschild & Co Redburn issued a Neutral rating with a revised price target of $420 in September 2025. Morgan Stanley previously upgraded Stryker Corp from Equal-weight to Overweight in December 2024. Meanwhile, Wolfe Research began its coverage in September 2024 with an Outperform rating.
SYK Stock at a Glance
In the latest trading session, Stryker Corp shares dipped 0.74% to close at $372.29. The stock fluctuated between a low of $370.4 and a high of $376.45 during the day. Over the last five sessions, shares rose by approximately 2.21%, but year-to-date performance shows a decline of about 3.26%.
Stryker reached a 52-week high of $406.19 on January 28, 2025, and a low of $329.16 on April 7, 2025, highlighting a wide performance range over the past year.
Key Levels to Watch
The 24-hour chart reveals a support level at 369.64; a fall below this could send prices toward 367.00. Resistance is standing firm at 375.69, with a secondary ceiling at 379.10. The 14-day RSI registers at 54.35, signaling neutral momentum and leaving room for movement in either direction.
Short Interest on the Rise
Short interest in Stryker Corp saw a significant increase as of November 14, 2025, jumping by 0.54 million shares to a total of 4.29 million. This represents a 12.55% rise from the 3.75 million shares reported on October 15, 2025. Although short shares make up only 2.53% of the overall float, the days-to-cover ratio has also reached 2.53, indicating growing bearish sentiment.
Institutional Interest and Price Targets
Analyst expectations remain generally optimistic. FactSet data shows an average 12-month price target of 414, suggesting a potential 10.38% increase from the prior close of $375.08. Some forecasts push the stock as high as 448 by 2025, with the lowest target at 400. By the end of 2025, 14 analysts rated Stryker as a Buy.
Earlier, on May 30, 2024, Goldman Sachs assigned a Neutral rating with a $372 price target as it initiated coverage on the stock.
